Article in Japanese

A case of pneumococcal meningitis with congenital diaphragmatic hernia and hypoplastic spleen

Haruna Tokitomo^1）, Hiroshi Okada^1）, Yuriko Yamashita^1）, Yuki Naruse^1）, Masato Mori^1）

Bacterial meningitis is a severe infectious disease with a high mortality rate and the potential for sequelae. While its incidence has decreased since the introduction of pneumococcal conjugated vaccine into the routine immunization program, pneumococcal meningitis is still caused by serotypes not included in the vaccine. Splenic hypofunction is an important risk factor for invasive pneumococcal disease such as meningitis. This study reports a case with a history of congenital diaphragmatic hernia repair that developed pneumococcal meningitis, and was found to have splenic hypoplasia. In children with a history of congenital diaphragmatic hernia, it is considered necessary to evaluate the size of the spleen over time to assess the risk of developing invasive pneumococcal diseases.

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1）Department of Pediatrics, Matsudo City General Hospital

Key words	pneumococcal meningitis, congenital diaphragmatic hernia, splenic hypoplasia, invasive pneumococcal disease
Received	November 22, 2025
Accepted	February 16, 2026

38 (2)：144─149,2026