Article in Japanese

Ampicillin was effective in the primary treatment of 2 cases of acute mastoiditis

Yukihiro MATSUKAWA^1,2), Eisuke ITO²⁾

Acute mastoiditis may develop as a complication of acute otitis media in healthy children. While there is no good evidence for the treatment of acute mastoiditis, the use of broad-spectrum antimicrobial agents is sometimes recommended. We herein report two cases of acute mastoiditis as a complication of otitis media in two pediatric patients at our hospital who were successfully treated with narrow-spectrum antimicrobial agents. Case 1: left acute mastoiditis developed in a 4-year-old female patient who recovered fully after treatment with an intravenous ampicillin infusion and amoxicillin. Case 2: bilateral acute mastoiditis developed in a 1-year-old male patient who recovered fully following treatment with an intravenous ampicillin infusion and amoxicillin.
For the treatment of acute mastoiditis, a narrow-spectrum antimicrobial agent should be chosen after due consideration of the risk of complications and antibiotic-resistant bacterial infection as well as the patient's general health.

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1) Department of Children's Cancer Center, National Center for Child Health and Development
2) Department of Pediatrics, Saiseikai Shigaken Hospital

Key words	acute mastoiditis, treatment, a narrow-spectrum antimicrobial agent
Received	May 9, 2019
Accepted	September 3, 2019

31 (4)：367─371,2019