Article in Japanese

Survey of antimicrobial prescribing in outpatient pediatric clinics in Hyogo prefecture

Hiroshi HACHIWAKA^{1, 2）}, Shota MYOJIN^3）, Jiro ABE^{1, 4）}, Yusuke ITO^{1, 5）}, Fumiko ORIYAMA^{1, 6）}, Mizutaka KAJIYAMA^{1, 7）}, Ken KOBAYASHI^{1, 8）}, Kazuko SUGIHARA^{1, 9）}, Kazuto TATSUMI^{1, 10）}, Hisako TANAKA^{1, 11）}, Satoru TSURUTA^{1, 12）}, Kyoichi NAKANISHI^{1, 13）}, Kiyoshi HAMAHIRA^{1, 14）}, Tetsuya MOMOTA^{1, 15）}, Kazunori MIKI^{1, 16）}, Chihiro YAMAMOTO^{1, 17）}, Mototsugu YOSHIDA^{1, 18）}, Takao OKAFUJI^{1, 19）}, Yasuhito TOMIMOTO^{1, 20）}, Takashi FUJITA^{1, 21）}, Masashi KASAI^{1, 3）}

In view of the appropriate use of antimicrobial agents, this survey on antimicrobial prescribing was conducted at twelve general pediatric clinics belonging to the Hyogo Pediatric Association. The rate of antimicrobial prescribing was 1.2% (89/7,603) overall, 1.3% (87/6,571) for acute respiratory tract infections, and 0.2% (2/1,032) for acute diarrhea. Details of the antimicrobial agents prescribed were amoxicillin (AMPC) in 59 patients (66.3%), amoxicillin clavulanic acid (AMPC/CVA) in 12 (13.5%), clarithromycin (CAM) in 8 (9.0%), third-generation cephalosporins in 4 (4.5%), tosufloxacin (TFLX) in 3 (3.4%), fosfomycin (FOM) in 2 (2.2%), and tebipenem pivoxil (TBPM-PI) in 1(1.1%). For acute respiratory tract infections, AMPC was prescribed for all acute pharyngitis and streptococcal infections. On the other hand, for acute otitis media, some clinics prescribed AMPC and others AMPC/CVA, while for rhinosinusitis, some clinics prescribed AMPC, CAM, and third-generation cephalosporins. FOM was prescribed in only two cases for acute diarrhea. In order to promote the appropriate use of antimicrobial agents, monitoring of antimicrobial prescriptions in the community and active discussion are effective.

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1）Infection Control Committee, Hyogo Pediatric Association
2）Hachiwaka Pediatric Clinic
3）Hyogo Prefectural Kobe childrenʼs Hospital
4）Department of Pediatrics, Hyogo Prefectural Nishinomiya Hospital
5）Department of Pediatrics, HyogoPrefectural Amagasaki General medical Center
6）Oriyama Pediatric Clinic
7）Kajiyama Pediatric Allergy Clinic
8）Kobayashi Pediatric Clinic
9）Sugihara Pediatric Clinic
10）Tatsumi Pediatric Clinic
11）Katada Clinic
12）Kobe City Medical Center General Hospital
13）Nakanishi Pediatric Clinic
14）Hamahira Pediatric Clinic
16）Department of Pediatrics, Itami City Hospital
17）Yamasiro Pediatric Clinic
18）Yoshida Pediatric Clinic
19）Okafuji Pediatric Clinic
20）Tomimoto Pediatric Clinic
21）Fujita Pediatric Clinic

Key words	antimicrobial agents, appropriate use, antimicrobial resistance (AMR), general pediatric clinics
Received	July 28, 2023
Accepted	March 13, 2024

36 (2)：111─119,2024