Article in Japanese

Two cases of human bocavirus infection requiring mechanical ventilation

Kazuki ASAI^1） , Masatoshi OSHIMA^1） , Ei KITANO^1） , Yasuo KITAGISHI^1） , Kazunori MORI^1） , Hiroki SOBAJIMA^1） , Takayuki AZUKIZAWA^1） , Toshie TAKAHASHI^1） , Yasuyo SIMIZU^1） , YuuKo ANZAI^1） , Masahito YAMAMOTO^1） , Seiro NARUMIYA^1）

Human bocaviruses (HBoV) are pathogens that can induce upper respiratory tract inflammation. Similar to respiratory syncytial viruses such as adenoviruses and rhinoviruses, HBoV can also cause acute bronchitis. Although most HBoV infections are not serious, there have been some reports of severe HBoV infections in children with underlying illness. We report on two cases of HBoV infection which occurred in premature and very low birth weight infants with a history of chronic lung disease requiring home oxygen therapy and mechanical ventilation. HBoV should be considered as part of the differential diagnosis when treating severe viral infections in children with underlying illness.

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1） Japanese Red Cross Society Nagahama Red Cross Hospital

Key words	human bocavirus, severe respiratory tract infection, ventilator management
Received	June 20, 2022
Accepted	November 30, 2022

34 (4)：299─305,2022