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Article in Japanese

A 13-year-old boy with the severe Jarisch-Herxheimer reaction accompanied by cardiac dysfuntion in the treatment of leptospirosis

Hiroyuki OIKAWA1,2), Takatoshi TSUCHIHASHI1), Masahiro BAMBA1)

This study reported a 13-year-old boy with warm shock accompanied by cardiac dysfunction. This symptom was caused by severe Jarisch-Herxheimer reaction(JHR) during treatment for leptospirosis. There are few reports of cardiac dysfunction related to the JHR. Although JHR is usually mild, there are some severe cases that could occur within a few hours after antibiotic treatment for leptospirosis, possibly resulting in shock. Close attention is warranted for JHR cases that are starting antibiotic treatment for leptospirosis.

1) Department of Pediatrics, Kawasaki Municipal Hospital
2) Department of Pediatrics, School of Medicine, Keio University

Key words Jarisch-Herxheimer reaction, leptospirosis, shock, cardiac dysfunction
Received December 18, 2018
Accepted March 20, 2019

31 (3):264─268,2019