The Journal of Pediatric Infectious Diseases and lmmunology Online Journal

Abstract

The Journal of Pediatric Infectious Diseases and Immunology > Vol.31 No.2 contents > Abstract

Article in Japanese

A case of norovirus infection with acute encephalopathy and septic shock

Nachika IKEDA1), Shinji KAWABE2), Kenta ITO1)

A previously healthy 11-year-old boy developed acute encephalopathy and septic shock through a norovirus infection. On the day of symptom onset, he developed fever and drowsiness. He was admitted subsequently to his previous hospital. On day 2, he was transferred to the Pediatric Intensive Care Unit of Aichi Children's Health and Medical Center because of vomiting, diarrhea, hypotension, and exacerbation of impaired consciousness. Results of the immunochromatographic test for the rapid detection of norovirus and bacterial cultures of his blood and cerebrospinal fluid were negative. An electroencephalogram showed diffuse high-amplitude slow waves (1~2 Hz) at the frontal region. On day 4, he was extubated, and inotropic agents were discontinued. On day 12, he was discharged from the hospital without any sequela. After discharge, polymerase chain reaction detected the GII-2 norovirus genome in his stool, which was submitted to the Public Health Center.


1) Department of General Pediatrics, Aichi Children's Health and Medical Center
2) Department of Infection and Immunology, Aichi Children's Health and Medical Center

Key words norovirus, acute encephalopathy, septic shock
Received October 18, 2018
Accepted February 26, 2019

31 (2):157─162,2019

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