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The Journal of Pediatric Infectious Diseases and Immunology > Vol.30 No.1 contents > Abstract

Article in Japanese

Microbiological study of 314 cases of idiopathic intussusception: possibility of causative parechovirus in infants

Chiharu MATSUBARA1), Tomoki SATO2), Hiroyuki SHIMOZONO2), Keita MATSUBARA2)

Intussusception is the most common disease causing intestinal obstruction in children. Although the cause of idiopathic intussusception is not disclosed at present, intussusception suggests a relationship with preceding infection. This study was aimed to clarify the relationship between the fecal specimen and intussusception patients. Bacteriologic or virological examination was performed using stool specimens from patients diagnosed with intussusception. Identification of bacteria and virus was carried out using stool and cell culture, PCR, RT-PCR, EIA and electron microscopy.
In the results, 315 cases received a diagnosis of intussusception between 2009 and 2015. A single viral pathogen was detected in 144 cases. Although adenovirus accounted for the majority of cases at all ages, parechovirus occupied 28.9% in patients under 1 year old. It was suggested that parechovirus was involved in the development of idiopathic intussusception in infants under 1 year of age.

1) Division of Neonatal Medicine, Hiroshima City Hiroshima Citizens Hospital
2) Department of Pediatrics, Hiroshima City Funairi Citizens Hospital

Key words parechovirus, adenovirus, infants, intussusception
Received August 2, 2017
Accepted February 8, 2018

30 (1):26─32,2018