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The Journal of Pediatric Infectious Diseases and Immunology > Vol.29 No.2 contents > Abstract

Article in Japanese

A case of non-herpetic acute limbic encephalitis by influenza in which examination of the cerebrospinal fluid, imaging study and EEG were normal

Kayo KITA1), Hirotaka MOTOI2), Yoshihiro WATANABE2), Youichi KABURAKI1), Yoshinori KOBAYASHI1)

A 13 year-old girl presented disturbance of orientation after alleviating fever in the emergency room. Examination of cerebrospinal fluid, magnetic resonance imaging (MRI) of the head and electro encephalography (EEG) were normal. The disturbance of orientation episode resolved itself with no treatment. A blood sample and the cerebrospinal fluid were positive for anti-NMDA-receptor antibody, leading to the diagnosis of non-herpetic acute limbic encephalitis (NHALE), which often leaves neurological after effects. Therefore, early treatment of initially diagnosed non-herpetic acute limbic encephalitis is essential.

1) Department of Pediatrics, National Hospital Organization Yokohama Medical Center
2) Children's Medical Center, Yokohama City University Medical Center

Key words
Received November 14, 2016
Accepted March 27, 2017

29 (2):160─164,2017