Article in Japanese

A case of non-herpetic acute limbic encephalitis by influenza in which examination of the cerebrospinal fluid, imaging study and EEG were normal

Kayo KITA¹⁾, Hirotaka MOTOI²⁾, Yoshihiro WATANABE²⁾, Youichi KABURAKI¹⁾, Yoshinori KOBAYASHI¹⁾

A 13 year-old girl presented disturbance of orientation after alleviating fever in the emergency room. Examination of cerebrospinal fluid, magnetic resonance imaging (MRI) of the head and electro encephalography (EEG) were normal. The disturbance of orientation episode resolved itself with no treatment. A blood sample and the cerebrospinal fluid were positive for anti-NMDA-receptor antibody, leading to the diagnosis of non-herpetic acute limbic encephalitis (NHALE), which often leaves neurological after effects. Therefore, early treatment of initially diagnosed non-herpetic acute limbic encephalitis is essential.

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1) Department of Pediatrics, National Hospital Organization Yokohama Medical Center
2) Children's Medical Center, Yokohama City University Medical Center

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Received	November 14, 2016
Accepted	March 27, 2017

29 (2)：160─164,2017