Article in Japanese

Five cases of human parvovirus B19 infection with vascular purpura

Tomowa KANOU¹⁾, Yutaka YOSHIMATSU¹⁾, Naohiko MORIGUCHI¹⁾

Human parvovirus B19 (PVB19) infection is occasionally accompanied by purpura that is classified as thrombocytopenic and non-thrombocytopenic. This study presented five cases of PVB19 infection including one case of papular-purpuric "gloves and socks" syndrome (PPGSS) with non-thrombocytopenic purpura being reported. Two male and three female patients aged between 2 and 13 years, with infections demonstrated by PVB19 IgM-positive results or PVB19-DNA detection, were included in this study. In the cases of non-thrombocytopenic purpura with PVB19, petechiae of 1-3 mm appeared in the extremities and trunk during the early stage of infection. Of the five patients, one received prednisolone (PSL) for abdominal pain, while the other four showed natural remission without medication. Since serum complement titers were lowered transiently in two cases, and leukopenia developed in four, PVB19 infection should be considered when fine purpura develops in the extremities and trunk with low serum complement titers or leukopenia.

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1) Department of Pediatrics, Kindai University Sakai Hospital

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Received	June 20, 2016
Accepted	May 8, 2017

29 (2)：148─152,2017