Article in Japanese
Two cases of urinary tract infection caused by Staphylococcus saprophyticus in children
Michiko MYOKAI1), Masayoshi SHINJOH2), Tsutomu KAMIMAKI1)
Staphylococcus saprophyticus is a species of coagulase negative staphylococci (CNS), and is well known as the second most frequent causative organism of cystitis in females. However, it is not a common causative organism of urinary tract infection in males or children. This study reports two cases of urinary tract infection caused by S. saprophyticus in children.
Case 1: A 9-year-old male having spina bifida presented with 2 days of fever and anorexia at the authors' hospital. Urinalysis showed 5-9 white blood cells (WBC) per high power field (hpf), and Gram positive cocci were seen in the Gram stein of urine. Urine culture on the day of admission and second day in hospital showed pure S. saprophyticus growth of 104 colony for unit (CFU)/ml and 102 CFU/ml, respectively. The patient was treated successfully with vancomycin for 5 days, followed by trimethoprim-sulfamethoxazole for 9 days.
Case 2: A previously healthy 3-year-old female presented with a few days of pain when urinating at the authors' hospital. Urinalysis showed>100 WBC per hpf. Gram stein of urine was not performed. Urine culture showed pure S. saprophyticus growth of 107 CFU/ml. The patient was treated successfully with 7 days of tosufloxacin.
S. saprophyticus is not only a causative organism of cystitis in young women, but also one of urinary tract infection, even in children. All CNS isolated from urine should not be regarded as contamination.
1) Department of Pediatrics, Shizuoka City Shimizu Hospital
2) Department of Pediatrics, Keio University School of Medicine
|Received||April 15, 2015|
|Accepted||June 29, 2015|