Article in Japanese

Streptococcus pneumoniae isolation and antimicrobial susceptibility in pediatrics department of a hospital during the recent 5 years

Masahiro KAWAGUCHI, Naoko NISHIMURA, Suguru TAKEUCHI, Fumihiko HATTORI, Kazuhiro HORIBA, Kensei GOTOH, Haruki HOSONO, Koji TAKEMOTO, Takao OZAKI

We investigated 955 Streptococcus pneumoniae strains isolated from 955 patients who attended the Pediatrics Department of Konan Kosei Hospital during the recent 5 years (2008-2012). About 70% of all isolates were obtained from children aged 0-3 years old, and the number of the isolates showed a tendency to decrease after 2010. Although the PCG resistance (PISP+PRSP) rate was around 60% until 2010, it showed a decrease to 46% in 2011 and decreased further to 32% in 2012. In contrast, no changes were noted in the MICs of 22 other antimicrobial agents. Invasive S. pneumoniae infection was found in 23 patients (2.4%). Among 13 isolates of them investigated for capsular serotypes, 10 strains (77%) had serotypes covered by the 13-valent pneumococcal conjugate vaccine (PCV13).

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Department of Pediatrics, Konan Kosei Hospital

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Received	July 4, 2014
Accepted	September 1, 2014

26 (4)：439─445,2015