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Article in Japanese

Adverse reactions to gamma globulin infusion in an atypical case of X-linked agammaglobulinemia with anti-IgA antibody diagnosed during adulthood

Masaru SHIMURA, Shinichiro MORICHI, Souken GO, Yasuyo KASHIWAGI, Hisashi KAWASHIMA

Intravenous immunoglobulin replacement therapy is necessary for primary antibody deficiencies, but it has the risk of potential side effects. A number of adverse reactions have been reported as primary immunodeficiency diseases. We reported a case of X-linked hypogammaglobulinemia with anti-IgA antibody diagnosed suffered from side effects on each IVIG. In immunodeficiencies patients, it has been considered that the reaction rate is very low. It is necessary to discuss countermeasures for cases with adverse reactions.

Department of Pediatrics, Tokyo Medical University

Key words
Received October 21, 2013
Accepted July 3, 2014

26 (3):381─385,2014