The Journal of Pediatric Infectious Diseases and lmmunology Online Journal


The Journal of Pediatric Infectious Diseases and Immunology > Vol.25 No.4 contents > Abstract

Article in Japanese

Adverse events and adverse reactions after vaccination

Kiyotaka OHTANI1), Jun MORITA2), Jun ABE3), Noboru MATSUMOTO4), Osamu KOBAYASHI5), Ryuta ITAKURA6), Ken HAYASHI7), Toshihiro TANAKA8), Akihiko SAITOH9)

The objective of vaccination is to protect children from vaccine preventable diseases (VPDs). It is indispensable to provide vaccination to all infants in their early age. However, adverse reactions and lack of accurate information of vaccination make certain vaccines suspended or not recommended in Japan. Persistent pain after human papillomavirus (HPV) vaccine and sudden death after simultaneous vaccination including Haemophilus influenzae type b (Hib) vaccine and pneumococcal conjugate vaccine (PCV7) were recent issues.
Adverse events surveillance program, such as Vaccine Adverse Event Reporting System (VAERS) in the United States does not exist in Japan. As vaccine distributed widely, the benefits of vaccination have become more difficult to realize because the incidence of VPDs decreased and adverse reactions started to stand out relatively. Potential problems of adverse reactions are not only people not to receive the benefit of vaccination but also reports misinformation by the mass media. In order to solve the issues, we need to build a system to grasp between the adverse reactions and adverse events to accumulate evidence. It is important that we deliver the efficacy, effectiveness and safety of vaccination to citizens and mass media continuously. We hope that better understanding of vaccination helps to the bright future of Japanese children.

1) Department of Pediatrics, Sagamihara Kyodo Hospital
2) Smile Children's Clinic
3) Department of Pediatrics, Saga?ken Medical Centre Koseikan
4) Department of Pediatrics, Saitama Medical Center
5) Department of Pediatrics, Nishida Hospital
6) Shizuoka Children's Hospital
7) Nagano Children's Hospital
8) Department of Pediatrics, Shizuoka Kosei Hospital
9) Department of Pediatrics, Niigata University Graduate School of Medical and Dental Sciences

Key words
Received January 1, 1970
Accepted January 1, 1970

25 (4):481─488,2014