Article in Japanese

A case report of clinically mild encephalitis with a reversible splenial lesion caused by mumps virus infection

Toru WATANABE

This study reports the case of a 7-year-7-month old boy demonstrating clinically mild encephalitis with a reversible splenial lesion caused by the mumps virus infection. He suffered from fever, and disturbed consciousness. On day 1, he started to vomit. On day 2, he developed a fever. He had a persistently high temperature and was admitted to our hospital on day 3 with disturbed consciousness. The fever continued after admission. A brain MRI showed high intensity lesions in the splenium of the corpus callosum. He was treated with steroid pulse therapy and an anti epileptic drug. Mumps virus was detected in the pharynx and cerebrospinal fluid, and mumps virus antibody titers were elevated in his serum. Therefore, MERS caused by mumps virus infection was diagnosed. The boy has suffered no sequelae, to date. This study also reported the cytokines and biomarkers of serum and CSF, by comparing those before and after the steroid pulse therapy.

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Department of Pediatrics, Iwata City Hospital

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Received	August 28, 2013
Accepted	November 20, 2013

25 (4)：433─438,2014