Article in Japanese

Clinical analysis of childhood urinary tract infection due to extended-spectrum β-lactamase producing Escherichia coli and Klebsiella pneumoniae

Akio FURUSE, Koji NAGANO, Satoshi KOMAKI, Hanae MOCHINAGA, Mio SAITOU

Twenty five pediatric cases of urinary tract infection, due to extended-spectrum β-lactamase (ESBL) producing bacteria were retrospectively evaluated concerning to clinical pictures, urinary abnormalities, presence of underlying disease such as congenital anomalies of the kidney urinary tract (CAKUT) and prognosis. From 25 cases, 30 specimens of ESBL-producing bacteria were identified. They include 28 Escherichia coli and 2 Klebsiella pneumoniae isolates. Twelve cases were treated with prophylactic antibiotics and 14 cases showed CAKUT including vesicouretoral reflux (VUR) and hydro-nephrosis. Our data suggest that if we have a chance to detect the cases of UTI due to ESBL-producing bacteria, we should consider changing and／or stopping prophylactic antibiotics and select the operation for the underlying disease such as VUR.

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Department of Pediatrics, Kumamoto Chuo Hospital

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Received	October 11, 2012
Accepted	August 5, 2013

25 (4)：403─406,2014