Article in Japanese

Hepatitis B and C in Japan, past, present, and future

Jun HAYASHI

New infections of HBV and HCV are decreased. Unfortunately, de novo hepatitis B occurs among patients with prior resolution of HBV infection and HBV genotype A, along with human deficiency virus, is introduced to Japan from Europe and the U. S. by sexual transmission. The nucleocid analog drugs (lamivudine, adefovir, entecavir) are effective for patients with chronic hepatitis B, however, the appearance of drug-resistant HBV by long-term treatment are problems. Pegylated Interferonα+ribavirin is effective for patients with chronic hepatitis C of genotype 2 and added telaprevir (protease inhibitor of HCV) is effective for those of genotype 1.

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Center of General Medicine, Haradoi Hospital

Key words
Received	January 1, 1970
Accepted	January 1, 1970

25 (3)：309─314,2013