Article in Japanese

A case of serotype 24F pneumococcal meningitis after single inoculation of heptavalent pneumococcal conjugate vaccine

Mana HARADA¹⁾, Asuka NAKAMURA¹⁾, Tsubasa LEE¹⁾, Takahiro NIIZUMA¹⁾, Keiji KINOSITA¹⁾, Kaoru OBINATA²⁾, Kazunori OISHI³⁾, Akihito WADA⁴⁾, Naruhiko ISHIWADA⁵⁾, Toshiaki SHIMIZU⁶⁾

A one year five month old female infant developed pneumococcal meningitis one month after the first inoculation of heptavalent pneumococcal conjugate vaccine (PCV7). The pneumococcal serotype was 24F which was non-vaccine serotypes (NVT) not included in PCV7. She recovered immediately without sequelae by conventional therapy. Rare serotype such as 24F is not included in PCV13 or PPV23. It is forewarned that invasive pneumococcal disease by non-vaccine serotypes would increase in Japan.

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1) Department of Pediatrics, Koshigaya Municipal Hospital
2) Department of Pediatrics, Juntendo University Urayasu Hospital
3) International Center for Infectious Diseases, Research Institute for Microbial Diseases, Osaka University
4) Department of Bacteriology, National Institute of Infectious Diseases
5) Division of Control and Treatment of Infectious Diseases, Chiba University Hospital
6) Department of Pediatrics, Juntendo University Faculty of Medicine

Key words
Received	September 22, 2011
Accepted	March 12, 2012

24 (3)：253─257,2012