Article in Japanese

Oxidative stress biomarkers

Hirokazu TSUKAHARA

Oxidative stress plays a critical role in infectious, inflammatory, allergic, and other various pediatric diseases. Rapidly progressive or chronic persistent conditions in these diseases might cause destructive changes in tissues and organs of the human body. Therefore, redox modulating agents might be the promising therapeutic tools for oxidative-stress related diseases. This review is intended to describe a list of clinically applicable oxidative stress biomarkers, linkage of enhanced oxidative stress with altered nitric oxide production and endothelial dysfunction syndrome, and future directions of oxidative stress biomarkers in the pediatric clinical field.

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Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

Key words
Received	January 1, 1970
Accepted	January 1, 1970

24 (2)：181─189,2012