Article in Japanese

Severe enterovirus infection with different clinical presentation in twin neonates

Takayuki KANEKO^1,2), Tomohiro OISHI²⁾, Takatoshi SHIRAI²⁾, Jun NEGISHI²⁾, Mai MATSUO²⁾, Shinya TSUKANO²⁾, Tetsuo TAGUCHI²⁾, Makoto UCHIYAMA¹⁾

Enteroviruses are common causes of infections in neonates. The clinical presentation may vary from mild illness to severe multisystem disease, such as sepsis, meningitis and myocarditis. We report severe enterovirus infection in twin neonates. One of them had meningitis, another had myocarditis and arrhythmia. Both were treated with intravenous immunoglobulin, and made a complete recovery. We consider that the differences of onset and route of infection may affect the different clinical presentation.

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1) Department of Pediatrics of Niigata University
2) Department of Pediatrics of Niigata Prefectural Shibata Hospital

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Received	August 24, 2010
Accepted	March 24, 2011

23 (2)：155─161,2011