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Article in Japanese

IRAK4 deficiency and infection

Hidetoshi TAKADA

According to the recent findings of the molecular mechanism in innate immunity, some new primary immunodeficiency diseases have been clarified. Ten diseases are included in IUIS (International Union of Immunological Societies) classification of primary immunodeficiency. Among them, IRAK4 deficiency and MyD88 deficiency, both of which are closely related in clinical and pathophysiological point of view are described here.

Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University

Key words
Received January 1, 1970
Accepted January 1, 1970

23 (1):81─87,2011